ESR 2.5
Identification of Multi-Drug-Resistant Organisms (MDRO) in Refugees

Project

Antimicrobial resistance is emerging worldwide. The role of human migration in the transmission of infectious diseases is established but the role of one of the current, most significant influxes of migrants and refugees in Europe’s history is largely unknown. Carriage rates of MDRO in asylum seekers with no hospitalizations in their countries may be higher than in the Dutch population, but might actually be lower than in Greece, at least for Gram-negatives. The PhD student studies the carriage rate of migrants in different geographical settings and the change in carriage rate of antimicrobial resistant microorganisms and microbiomes over time.

Supervisors

Collaborations

Check-points, the Netherlands

Relevant publications

  1. Ravensbergen SJ, Lokate M, Cornish D, Kloeze E, Ott A, Friedrich AW, et al. High Prevalence of Infectious Diseases and Drug-Resistant Microorganisms in Asylum Seekers Admitted to Hospital; No Carbapenemase Producing Enterobacteriaceae until September 2015. PLoS One. 2016 May 4;11(5).
  2. Pournaras S, Poulou A, Tsakris A. Inhibitor-based methods for the detection of KPC carbapenemase-producing Enterobacteriaceae in clinical practice by using boronic acid compounds. J Antimicrob Chemother [Internet]. 2010;65(7):1319–21.
  3. Pournaras S, Zarkotou O, Poulou A, Kristo I, Vrioni G, Themeli-Digalaki K, et al. A combined disk test for direct differentiation of carbapenemase-producing Enterobacteriaceae in surveillance rectal swabs. J Clin Microbiol. 2013;51(9):2986–90.

Keywords

Refugees, Multi-drug resistant microorganisms, transmission, Carbapenemases